Search results for "Interaction studies"
showing 3 items of 3 documents
Pentafluorophenyl salicylamine receptors in anion–π interaction studies
2012
A crystal structure analysis confirms the appropriateness of pentafluorophenyl salicylamine (1a) as a π-acceptor for anion–π interactions. Crystals of 1a·HCl show that the OH-group fixes the anion in a η2-type binding motif above the electron-deficient arene. Attempts to find some relevance for this weak intermolecular force in solution failed. Stronger CH–, NH– and OH–anion interactions are dominant over the weak anion–π interactions. Due to the hydrogen bonding, the non-fluorinated receptor exhibits the highest binding constants within this series.
Conversion of the Sensor Kinase DcuS to the Fumarate Sensitive State by Interaction of the Bifunctional Transporter DctA at the TM2/PAS
2021
The membrane-bound C4-dicarboxylate (C4DC) sensor kinase DcuS of Escherichia coli typically forms a protein complex with the C4DC transporter DctA. The DctA × DcuS complex is able to respond to C4DCs, whereas DcuS without DctA is in the permanent ON state. In DctA, the C-terminal helix 8b (H8b) serves as the site for interaction with DcuS. Here the interaction site in DcuS and the related structural and functional adaptation in DcuS were determined. The Linker connecting transmembrane helix 2 (TM2) and the cytosolic PASC (Per-ARNT-SIM) domain of DcuS, was identified as the major site for interaction with DctA-H8b by in vivo interaction studies. The Linker is known to convert the piston-type…
Plasma-wall interaction studies within the EUROfusion consortium: Progress on plasma-facing components development and qualification
2017
This work has been carried out within the framework of the EUROfusion Consortium and has received funding from the Euratom research and training programme 2014-2018 under grant agreement No 633053. The views and opinions expressed herein do not necessarily reflect those of the European Commission.